Design for Six Sigma is a design methodology. It works if properly instituted and executed. Wrongly designing and forcefully applying can cause more harm than help. If we need to implement Design for Six Sigma we should do it at the primary levels and not during the mid or operating level. To know more about this topic, go through Alan Nicol (Executive Member, AlanNicolSolutions)'s article link: http://www.manufacturing.net/articles/2012/04/wrongly-doing-design-for-six-sigma